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Meghan Markle's half sister, Samantha, is in the hospital after suffering what appears to be a broken ankle and a fractured knee after a confrontation with the paparazzi ... TMZ has learned.

Samantha's boyfriend, Mark, tells TMZ, they were driving in Florida near a toll booth when they had a "paparazzi confrontation." He says the photog veered in front of them, trying to get a clear shot.