The new coronavirus variant Omicron has now become dominant in South Africa and is driving a sharp increase in new infections, health officials say.
Some 11,500 new Covid infections were registered in the latest daily figures.
That is a sharp rise on the 8,500 cases confirmed the previous day.
By contrast, daily infections were averaging between 200 and 300 in mid-November, a top South African scientist told the BBC.
Omicron has now been detected in at least 24 countries around the world, according to the World Health Organization (WHO).
People previously infected with other variants of coronavirus do not appear to be protected against Omicron but vaccines are still believed to protect against severe disease, according to top scientists from the global health body and South Africa's National Institute for Communicable Diseases.
The full picture in South Africa will not become clear until "people get so sick that they need to go to hospital" which is generally "three, four weeks later," says Prof Salim Abdool Karim of the Africa Task Force for Coronavirus.
"But the feedback we're getting from the ground is that there's really no red flags - we're not seeing anything dramatically different, what we're seeing is what we are used to," he told the BBC's Newsday programme.
The BBC's Pumza Fihlani in South Africa's biggest city, Johannesburg, says that restaurants and supermarkets remain packed, ahead of the Christmas and New Year holidays. People are talking about the new variant - but so far there's little panic and, according to scientists, there shouldn't be.
South Africa was the first country to report on the highly mutated new variant. Its National Institute for Communicable Diseases (NICD) has said more than 70% of all the virus genomes it sequenced last month have been of the new variant.
India, Ghana, Saudi Arabia and the UAE are among the latest countries to have confirmed their first cases of Omicron. Others including the UK, US and Germany have also seen people infected by the new variant.
Many questions about Omicron remain to be answered, including how much protection current vaccines provide.
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