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Ghana coach, Kwesi Appiah has dropped four key players ahead of the 2021 Africa Cup of Nations qualifiers against South Africa, according to Kumasi Oyerepa FM.

Asamoah Gyan, Kwadwo Asamoah, Christian Atsu and John Boye have all been left out of Ghana's squad to face South Africa and Sao Tome and Principle.

Ghana will start their 2021 Africa Cup of Nations qualifiers campaign with the Bafana Bafana of South Africa at the Cape Coast Sports Stadium on November 14.

According to reports, the Newcastle United winger has communicated to the technical handlers he would want to attend to his recurring knee injury.

The four-time AFCON champions will fly out to face Sao Tome and Principle in their Group C second game on November 17th.

The final list for the two matches will be released by Wednesday 30th October, 2019 by the Ghana Football Association.