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Lionel Messi waited over a month to make his home debut for Paris Saint-Germain and certainly didn't expect it to end with him being substituted as his team desperately chased a winner against Lyon.

Messi looked utterly bewildered when he was taken off for Achraf Hakimi in the 76th minute and didn't try to hide his anger, staring at the floor as he trod off, giving Mauricio Pochettino a deathly stare as he made for the bench and then snubbing the coach's offer of a handshake.

Pochettino's decision was vindicated as Mauro Icardi's injury-time winner clinched a 2-1 victory but Messi's dismayed reaction to the substitution was the main takeaway from the game and the overriding talking point.

Messi is not used to being substituted but he has now been taken off by Pochettino as many times as in each of his final three seasons at Barcelona, while he was not taken off in any league games in 2017/18 campaign.

Pochettino justified the decision after the game by saying he did not want to risk Messi getting injured but he made a bold move in taking off the six-time Ballon d'Or winner in a clear indication that the team's needs must come ahead of the needs of star players. 

Messi has a long history of defying coaches, even ones as imposing as Pep Guardiola and Luis Enrique, and Pochettino will need a firm backbone to dare take the player off again without consulting him.

Sportsmail takes a look at the other times coaches have made decisions Messi did not agree with. Each time, the Argentine ended up winning the battle with his manager.